Obama campaign spokesman Bill Burton:

Today, John McCain put the former mayor of a town of 9,000 with zero foreign policy experience a heartbeat away from the presidency. Governor Palin shares John McCain's commitment to overturning Roe v. Wade, the agenda of Big Oil and continuing George Bush's failed economic policies -- that's not the change we need, it's just more of the same.

McCain campaign spokesperson Jill Hazelbaker:

It is pretty audacious for the Obama campaign to say that Governor Palin is not qualified to be Vice President. She has a record of accomplishment that Senator Obama simply cannot match. Governor Palin has spent her time in office shaking up government in Alaska and actually achieving results -- whether it's taking on corruption, passing ethics reform or stopping wasteful spending and the 'bridge to nowhere.' Senator Obama has spent his time in office running for President.

And McCain senior advisor Nancy Pfotenhauer just said on Fox - and I'm paraphrasing: I think the Obama campaign would have learned not to belittle women.

Fasten your seat belts. We're in for a very bumpy ride.

Question: What is Hillary going to say?

UPDATE: The their surrogates attack the pick, the Democratic ticket is taking a different approach with this statement from Senators Obama and Biden:

We send our congratulations to Governor Sarah Palin and her family on her designation as the republican nominee for Vice President. It is yet another encouraging sign that old barriers are falling in our politics. While we obviously have differences over how best to lead this country forward Governor Palin is an admirable person and will add a compelling new voice to this campaign.